Quantum Dots for Cancer Research: Current Status, Remaining Issues, and Future Perspectives

Autor: Min Fang, Chun-wei Peng, Dai-Wen Pang, Yan Li
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Cancer Biology & Medicine, Vol 9, Iss 3, Pp 151-163 (2012)
Druh dokumentu: article
ISSN: 2095-3941
DOI: 10.3969/j.issn.2095-3941.2012.03.001
Popis: Cancer is a major threat to public health in the 21st century because it is one of the leading causes of death worldwide. The mechanisms of carcinogenesis, cancer invasion, and metastasis remain unclear. Thus, the development of a novel approach for cancer detection is urgent, and real-time monitoring is crucial in revealing its underlying biological mechanisms. With the optical and chemical advantages of quantum dots (QDs), QD-based nanotechnology is helpful in constructing a biomedical imaging platform for cancer behavior study. This review mainly focuses on the application of QD-based nanotechnology in cancer cell imaging and tumor microenvironment studies both in vivo and in vitro, as well as the remaining issues and future perspectives.
Databáze: Directory of Open Access Journals