Autor: |
Ans Timmermans, Melanie C Melendrez, Youry Se, Ilin Chuang, Nou Samon, Nichapat Uthaimongkol, Chonticha Klungthong, Wudtichai Manasatienkij, Butsaya Thaisomboonsuk, Stuart D Tyner, Sareth Rith, Viseth Srey Horm, Richard G Jarman, Delia Bethell, Nitima Chanarat, Julie Pavlin, Tippa Wongstitwilairoong, Piyaporn Saingam, But Sam El, Mark M Fukuda, Sok Touch, Ly Sovann, Stefan Fernandez, Philippe Buchy, Lon Chanthap, David Saunders |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
PLoS ONE, Vol 11, Iss 3, p e0152529 (2016) |
Druh dokumentu: |
article |
ISSN: |
1932-6203 |
DOI: |
10.1371/journal.pone.0152529 |
Popis: |
Little is known about circulation of influenza and other respiratory viruses in remote populations along the Thai-Cambodia border in western Cambodia. We screened 586 outpatients (median age 5, range 1-77) presenting with influenza-like-illness (ILI) at 4 sentinel sites in western Cambodia between May 2010 and December 2012. Real-time reverse transcriptase (rRT) PCR for influenza was performed on combined nasal and throat specimens followed by viral culture, antigenic analysis, antiviral susceptibility testing and full genome sequencing for phylogenetic analysis. ILI-specimens negative for influenza were cultured, followed by rRT-PCR for enterovirus and rhinovirus (EV/RV) and EV71. Influenza was found in 168 cases (29%) and occurred almost exclusively in the rainy season from June to November. Isolated influenza strains had close antigenic and phylogenetic relationships, matching vaccine and circulating strains found elsewhere in Cambodia. Influenza vaccination coverage was low ( |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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