The role of late reperfusion in ST-segment elevation myocardial infarction: a real-world retrospective cohort study

Autor: Qixin Guo, Jinyu Huang, Yong Shen, Guoxin Tong, Hong Li, Shasha Meng
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-020-01479-0
Popis: Abstract Background Early reperfusion of the coronary artery has become the first choice for patients with ST-segment elevation myocardial infarction (STEMI). How to deal with patients who miss the time window for early reperfusion is still controversial. Based on real-world data, this study was conducted to explore whether percutaneous coronary intervention (PCI) has an advantage over standard drug therapy in patients who miss the optimal treatment window. Methods Consecutive patients who were diagnosed with STEMI and met the inclusion criteria between 2009 and 2018 in our center were retrospectively included in this cohort study. The primary endpoint events were major adverse cardiac events (MACEs), including heart failure, sudden cardiac death, malignant arrhythmia, thrombi and bleeding events during the period of admission. Secondary endpoint events were components of MACEs. At the same time, we also evaluated angina pectoris at admission and discharge through Canadian Cardiovascular Society (CCS) grading. Results This study enrolled 417 STEMI patients and divided them into four groups (PCI 7 days, 34.29%; MED, 29.74%). During the period of admission, MACEs occurred in 52 cases. The incidence of MACEs was 11.29, 7.95, 4.20 and 25.81% in the four respective groups (p
Databáze: Directory of Open Access Journals