Leading Pathogens Involved in Co-Infection and Super-Infection with COVID-19: Forensic Medicine Considerations after a Systematic Review and Meta-Analysis

Autor: Roberto Scendoni, Emanuele Bury, Isabella Lima Arrais Ribeiro, Mariano Cingolani, Roberto Cameriere, Anna De Benedictis, Francesco De Micco
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pathogens, Vol 12, Iss 5, p 646 (2023)
Druh dokumentu: article
ISSN: 2076-0817
DOI: 10.3390/pathogens12050646
Popis: The COVID-19 pandemic raised concerns about the potential for co-infection or over-infection with other respiratory infections, as they can complicate the diagnosis, treatment and prognosis of the disease. This is also a challenge for forensic pathologists, who may come across cases where the presence of co-infection or over-infection is suspected or confirmed, and it is important that they take this into account when determining the cause of death. The aim of this systematic review is to analyse the prevalence of each specific pathogen co-infecting or over-infecting patients with SARS-CoV-2 infection. In total, 575 studies were selected from the Scopus and Pub-Med online databases and 8 studies were included in a meta-analysis. Male gender, advanced age and nursing home care are risk factors associated with the development of co-infection, whereas age, tachypnoea, hypoxaemia and bacterial infection are predictors of mortality. Overall, however, having a SARS-CoV-2 infection does not represent a real risk for the development of co-infections/super-infections.
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