Assessment of photodynamic therapy as a salvage treatment for local failure after chemoradiotherapy or radiotherapy for esophageal cancer in patients aged 80 years or older

Autor: Michiko Nishikawa, Yoshinobu Yamamoto, Saeko Kushida, Taku Hirabayashi, Syunta Tanaka, Naoki Takegawa, Takuya Mimura, Hidetaka Tsumura, Ikuya Miki, Masahiro Tsuda
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2692-4609
DOI: 10.1002/deo2.167
Popis: Abstract Objectives Chemoradiotherapy (CRT) or radiotherapy (RT) alone is often the treatment of choice for elderly patients with esophageal cancer with the expectation of organ preservation. However, salvage treatment remains a problem when endoscopic resection is not indicated for local failure after CRT/RT. Photodynamic therapy (PDT) is indicated for local failure after CRT/RT, but there are few reports on its efficacy and safety in elderly patients. This study aimed to assess the outcome of PDT for local failure after CRT/RT for esophageal cancer in elderly patients. Methods This retrospective single‐center study included 42 patients who first underwent PDT between April 2013 and June 2021. Patients aged ≥80 and
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