Adaptive Servo-Ventilation: A Comprehensive Descriptive Study in the Geneva Lake Area

Autor: Chloé Cantero, Dan Adler, Patrick Pasquina, Christophe Uldry, Bernard Egger, Maura Prella, Alain Bigin Younossian, Antoine Poncet, Paola Soccal-Gasche, Jean-Louis Pepin, Jean-Paul Janssens
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Medicine, Vol 7 (2020)
Druh dokumentu: article
ISSN: 2296-858X
DOI: 10.3389/fmed.2020.00105
Popis: Background: Use of adaptive servo-ventilation (ASV) has been questioned in patients with central sleep apnea (CSA) and chronic heart failure (CHF). This study aims to detail the present use of ASV in clinical practice.Methods: Descriptive, cross-sectional, multicentric study of patients undergoing long term (≥3 months) ASV in the Cantons of Geneva or Vaud (1,288,378 inhabitants) followed by public or private hospitals, private practitioners and/or home care providers.Results: Patients included (458) were mostly male (392; 85.6%), overweight [BMI (median, IQR): 29 kg/m2 (26; 33)], comorbid, with a median age of 71 years (59–77); 84% had been treated by CPAP before starting ASV. Indications for ASV were: emergent sleep apnea (ESA; 337; 73.6%), central sleep apnea (CSA; 108; 23.6%), obstructive sleep apnea (7; 1.5%), and overlap syndrome (6; 1.3%). Origin of CSA was cardiac (n = 30), neurological (n = 26), idiopathic (n = 28), or drug-related (n = 22). Among CSA cases, 60 (56%) patients had an echocardiography within the preceding 12 months; median left ventricular ejection fraction (LVEF) was 62.5% (54–65); 11 (18%) had a LVEF ≤45%. Average daily use of ASV was [mean (SD)] 368 (140) min; 13% used their device
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