| Autor: |
Castro-Gamboa Ian, Cardoso Carmen L., Silva Dulce H. S., Cavalheiro Alberto J., Furlan Maysa, Bolzani Vanderlan da S. |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Journal of the Brazilian Chemical Society, Vol 14, Iss 5, Pp 771-776 (2003) |
| Druh dokumentu: |
article |
| ISSN: |
0103-5053 |
| Popis: |
Living cells are continuously exposed to a variety of challenges that exert oxidative stress and are directly related with senescence and the onset of various pathological conditions such as coronary heart disease, rheumatoid arthritis and cancer. Nevertheless, living organisms have developed a complex antioxidant network to counteract reactive species that are detrimental to life. With the aim of bio-prospecting plant species from the Brazilian Cerrado and Atlantic Forest, we have established a methodology to detect secondary antioxidant metabolites in crude extracts and fractions obtained from plant species. Combining HPLC with an electrochemical detector allowed us to detect micromolecules that showed antioxidant activities in Chimarrhis turbinata (DC) leaf extracts. Comparison with purified flavonoid standards led us to identify the compounds in their natural matrices giving valuable information on their antioxidant capacity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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