Episodes of Guillain-Barré syndrome associated with the acute phase of HIV-1 infection and with recurrence of viremia

Autor: Castro Gleusa de, Bastos Patrícia Gomes, Martinez Roberto, Figueiredo José Fernando de Castro
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: Arquivos de Neuro-Psiquiatria, Vol 64, Iss 3A, Pp 606-608 (2006)
Druh dokumentu: article
ISSN: 0004-282X
1678-4227
Popis: We report a severe case of Guillain-Barré syndrome (GBS) characterized by flaccid areflexive tetraplegia and signs of autonomic instability related to acute HIV-1 infection, and the occurrence of relapse episodes coinciding with the detection of HIV-1 RNA in blood during the phase of irregular treatment with antiretroviral agents. The patient has been asymptomatic for 3 years and has an HIV-1 load below the limit of detection. The recurrence of GBS in this case may be related to alterations of the immunologic response caused by disequilibrium in the host-HIV relationship due to the increase in HIV-1 viremia.
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