Nodular primary localized cutaneous amyloidosis: presentation of 2 case reports and literature review

Autor: Cláudia Rosado, Clarinda Neves, Raquel Cruz, Manuela Loureiro
Jazyk: English<br />Spanish; Castilian<br />Galician<br />Portuguese
Rok vydání: 2015
Předmět:
Zdroj: Galicia Clínica, Vol 76, Iss 4, Pp 171-172 (2015)
Druh dokumentu: article
ISSN: 0304-4866
1989-3922
DOI: 10.22546/34/805
Popis: The nodular primary localized cutaneous amyloidosis is rare and characterized by skin deposition of amyloid substance. There are cases of progression to invasive disease. The type of amyloid substance is not specific to this disease, also being found in primary systemic amyloidosis and systemic amyloidosis associated with multiple myeloma. The authors describe two cases of nodular primary localized cutaneous amyloidosis. A 70-year-old man underwent excision of papule on the mouth left commissure, and a 39-year-old woman with a vulva’s labia majora swelling that was excised, in which the histology revealed a nodular amyloidosis, both without systemic involvement. Although the prognosis is benign, the follow-up of the patient is required for early detection of a possible evolution to systemic disease, or exclusion of an underlying systemic amyloidosis.
Databáze: Directory of Open Access Journals