Impact of ultrasound limitation to assess aortitis in patients with giant cell arteritis: comparative study with FDG-PET/CT

Autor: Eugenio De Miguel, Julia Martínez-Barrio, Isabel Castrejón, Jose María Álvaro-Gracia, Elisa Fernández-Fernández, Juan Molina-Collada, Gabriela Torres Ortiz, Irene Monjo-Henry
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: RMD Open, Vol 9, Iss 3 (2023)
Druh dokumentu: article
ISSN: 2056-5933
DOI: 10.1136/rmdopen-2023-003329
Popis: Objective To determine the impact of ultrasound (US) intrinsic limitation to assess aortitis versus FDG-PET/CT in patients with US-proven giant cell arteritis (GCA) and to identify factors associated with aortic involvement.Methods Retrospective observational study of patients referred to US fast-track clinics at two academic centres over a 4-year period. Only patients with GCA confirmed by US were included. Temporal arteries (TA) and extracranial arteries US were performed at baseline. FDG-PET/CT was performed according to clinician’s criteria. An FDG artery uptake at the aorta higher than liver uptake was considered positive for aortitis.Results Seventy-two of 186 patients with US-proven GCA underwent an FDG-PET/CT; 29 (40.3%) had a positive FDG-PET/CT and 24 (33.3%) presented aortitis. Only 6 (20.7%) patients with positive FDG-PET/CT had negative US findings of large vessel (LV)-GCA. Among patients with aortitis in FDG-PET/CT, only two (8.3%) had negative US findings of LV-GCA. Patients with aortitis were younger (68.9 vs 81;p
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