Primary diffuse leptomeningeal gliomatosis: An autopsy case report
| Autor: | Shaik Afshan Jabeen, Arikapadu Haritha Chowdary, Rukmini Mridula Kandadai, Megha S. Uppin, Angamattu Kanikannan Meena, Rupam Borgohain, Challa Sundaram |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Annals of Indian Academy of Neurology, Vol 17, Iss 2, Pp 227-230 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0972-2327 1998-3549 |
| DOI: | 10.4103/0972-2327.132647 |
| Popis: | Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition, characterized by infiltration of the meninges by glial cells without evidence of the primary tumor in the brain or spinal cord parenchyma. Glioma arising primarily from the leptomeninges is extremely rare and often diagnosed only in post mortem examination and the diagnosis may be missed in meningeal biopsy. We describe a young female who presented with symptoms of raised intracranial pressure with imaging evidence of diffuse leptomeningeal enhancement in whom autopsy confirmed the diagnosis of PDLG. Our case illustrates the diagnostic difficulties in making the pre-mortem diagnosis even with multiple cerebrospinal fluid cytologies and leptomeningeal biopsy. |
| Databáze: | Directory of Open Access Journals |
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