Comparative performance and external validation of the multivariable PREDICT Prostate tool for non-metastatic prostate cancer: a study in 69,206 men from Prostate Cancer data Base Sweden (PCBaSe)

Autor: David Thurtle, Ola Bratt, Pär Stattin, Paul Pharoah, Vincent Gnanapragasam
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Medicine, Vol 18, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 1741-7015
DOI: 10.1186/s12916-020-01606-w
Popis: Abstract Background PREDICT Prostate is an endorsed prognostic model that provides individualised long-term prostate cancer-specific and overall survival estimates. The model, derived from UK data, estimates potential treatment benefit on overall survival. In this study, we externally validated the model in a large independent dataset and compared performance to existing models and within treatment groups. Methods Men with non-metastatic prostate cancer and prostate-specific antigen (PSA)
Databáze: Directory of Open Access Journals
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