The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

Autor: Eun Shik Choi, Youngseo Cheon, Keunsoo Kang, Daeyoup Lee
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-017-00704-3
Popis: The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.
Databáze: Directory of Open Access Journals