| Autor: |
Zofia Maciejewska-Szaniec, Marta Kaczmarek-Ryś, Szymon Hryhorowicz, Agnieszka Przystańska, Tomasz Gredes, Barbara Maciejewska, Justyna Hoppe-Gołębiewska, Ryszard Słomski, Andrzej Pławski, Agata Czajka-Jakubowska |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMC Oral Health, Vol 21, Iss 1, Pp 1-10 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1472-6831 |
| DOI: |
10.1186/s12903-021-01844-1 |
| Popis: |
Abstract Background Chronic stress is one of the leading predisposing factors in bruxism aetiology, but the influence of genetic factors is also suggested. We aimed to study whether sequence variants in genes involved in stress regulation pathways: NTRK2 and BDNF, may be associated with awake bruxism susceptibility, clinical presentation, and patients’ perceived stress level. Methods The study group included 104 patients with probable awake bruxism and 191 population controls. Patients underwent dental examination concerning the symptoms of bruxism and psychological testing. Genotyping was performed using HRMA and sequencing. Statistical analyses were conducted, and P values below 0.05 were considered statistically significant. Results We observed a positive correlation of measured stress level and pathological teeth attrition in the anterior segment (r = 0.45, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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