Associations between uric acid and depressive symptoms, and the mediating role of immunoinflammatory: Findings from rural older adults

Autor: Yating Luo, Sha Wang, Qinqin Cheng, Jing Li, Huiyi Zhang, Jingying Wang, Juan Luo, Chen Pan, Qiuxiang Zhang, Jianfei Xie, Andy S.K. Cheng
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100893- (2024)
Druh dokumentu: article
ISSN: 2666-3546
DOI: 10.1016/j.bbih.2024.100893
Popis: Abstracts: Background: In the low-resource rural areas, older adults may experience prolonged and severe depressive symptoms. This study aimed to investigate the relationship between uric acid, depressive symptoms and immunoinflammatory among rural older adults. Method: This case-control study was conducted in 17 rural villages in Hunan Province, China, between January 2023 and April 2024. This study included 180 participants: (1) Rural Older Adults with Depressive Symptoms group:90 patients with first-time diagnosed with depressive symptoms (Geriatric Depression Scale-15, GDS-15 ≥ 5 scores); (2) Control group: 90 individually matched (age and sex) healthy subjects (GDS-15
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