Autor: |
Zhi Xu, Shu Zhang, Lian-Shun Feng, Xiao-Ning Li, Guo-Cheng Huang, Yun Chai, Zao-Sheng Lv, Hui-Yuan Guo, Ming-Liang Liu |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
Molecules, Vol 22, Iss 7, p 1171 (2017) |
Druh dokumentu: |
article |
ISSN: |
1420-3049 |
DOI: |
10.3390/molecules22071171 |
Popis: |
A series of novel 8-OMe ciprofloxacin (CPFX)-hydrazone/azole hybrids were designed, synthesized, and evaluated for their in vitro biological activities. Our results reveal that all of the hydrozone-containing hybrids (except for 7) show potency against Mycobacterium tuberculosis (MTB) H37Rv (minimum inhibitory concentration (MIC): |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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