The optimal interval for post-vaccination serological test in infants born to mothers with positive hepatitis B surface antigen

Autor: Hongyu Huang, Xuhui Zhang, Yuqian Luo, Jie Chen, Jing Feng, Yimin Dai, Yali Hu, Yi-Hua Zhou
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 17, Iss 12, Pp 5585-5589 (2021)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2021.1992213
Popis: Postvaccination serologic testing (PVST) is utilized to monitor the success or failure of vaccination against hepatitis B virus (HBV) infection in infants of hepatitis B surface antigen (HBsAg) positive mothers. This secondary analysis of 1255 infants of HBsAg-positive mothers at 7–14 months age included in two prospective studies aimed to determine the optimal interval for PVST after three hepatitis B vaccine doses. HBsAg and anti-HBs were quantitatively tested with microparticle enzyme immunoassay. The average PVST interval was 3.8 ± 2.2 months. Overall, 1.7% (21/1255) infants had anti-HBs
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