The upper respiratory tract microbiota of healthy adults is affected by Streptococcus pneumoniae carriage, smoking habits, and contact with children

Autor: A. Cristina Paulo, João Lança, Sónia T. Almeida, Markus Hilty, Raquel Sá-Leão
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Druh dokumentu: article
ISSN: 2049-2618
DOI: 10.1186/s40168-023-01640-9
Popis: Abstract Background The microbiota of the upper respiratory tract is increasingly recognized as a gatekeeper of respiratory health. Despite this, the microbiota of healthy adults remains understudied. To address this gap, we investigated the composition of the nasopharyngeal and oropharyngeal microbiota of healthy adults, focusing on the effect of Streptococcus pneumoniae carriage, smoking habits, and contact with children. Results Differential abundance analysis indicated that the microbiota of the oropharynx was significantly different from that of the nasopharynx (P
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