| Autor: |
V. Parisi, R. Baldassarre, V. Ferrara, R. Ditaranto, F. Barlocco, R. Lillo, F. Re, G. Marchi, C. Chiti, F. Di Nicola, C. Catalano, L. Barile, M. A. Schiavo, A. Ponziani, G. Saturi, A. G. Caponetti, A. Berardini, M. Graziosi, F. Pasquale, I. Salamon, M. Ferracin, E. Nardi, I. Capelli, D. Girelli, J. R. Gimeno Blanes, M. Biffi, N. Galiè, I. Olivotto, F. Graziani, E. Biagini |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Cardiovascular Medicine, Vol 10 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2297-055X |
| DOI: |
10.3389/fcvm.2023.1184361 |
| Popis: |
BackgroundElectrocardiogram (ECG) has proven to be useful for early detection of cardiac involvement in Anderson-Fabry disease (AFD); however, little evidence is available on the association between ECG alterations and the progression of the disease.Aim and MethodsTo perform a cross sectional comparison of ECG abnormalities throughout different left ventricular hypertrophy (LVH) severity subgroups, providing ECG patterns specific of the progressive AFD stages. 189 AFD patients from a multicenter cohort underwent comprehensive ECG analysis, echocardiography, and clinical evaluation.ResultsThe study cohort (39% males, median age 47 years, 68% classical AFD) was divided into 4 groups according to different degree of left ventricular (LV) thickness: group A ≤ 9 mm (n = 52, 28%); group B 10–14 mm (n = 76, 40%); group C 15–19 mm (n = 46, 24%); group D ≥ 20 mm (n = 15, 8%). The most frequent conduction delay was right bundle branch block (RBBB), incomplete in groups B and C (20%,22%) and complete RBBB in group D (54%, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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