Development and verification of a nomogram for predicting the prognosis of resectable gastric cancer with outlet obstruction

Autor: Chengzhi Wei, Changhua Li, Xiaojiang Chen, Guoming Chen, Runcong Nie, Chongyu Zhao, Zhiwei Zhou, Yongming Chen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-022-10260-9
Popis: Abstract Background The prognosis of patients with gastric cancer (GC) with gastric outlet obstruction (GOO) after gastrectomy is highly variable. In this study, we aimed to develop a nomogram to predict the prognosis of these patients. Patients and Methods Data from 218 GC patients with GOO who underwent gastrectomy at Sun Yat-sen University Cancer Center were retrospectively collected as a training cohort. The data of 59 patients with the same diagnosis who underwent gastrectomy at the First Affiliated Hospital of Guangxi Medical University were collected as an external verification cohort. A nomogram for the overall survival (OS) was developed using the Cox regression model in the training cohort, which was validated in a verification cohort. Results Multivariate analysis showed that the surgical procedure (P
Databáze: Directory of Open Access Journals
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