| Autor: |
Kathryn L. Taylor, George Luta, Vasiliki Zotou, Tania Lobo, Richard M. Hoffman, Kimberly M. Davis, Arnold L. Potosky, Tengfei Li, David Aaronson, Stephen K. Van Den Eeden |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
BJUI Compass, Vol 3, Iss 3, Pp 226-237 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2688-4526 |
| DOI: |
10.1002/bco2.124 |
| Popis: |
Abstract Objectives In a prospective, comparative effectiveness study, we assessed clinical and psychological factors associated with switching from active surveillance (AS) to active treatment (AT) among low‐risk prostate cancer (PCa) patients. Methods Using ultra‐rapid case identification, we conducted pretreatment telephone interviews (N = 1139) with low‐risk patients (PSA ≤ 10, Gleason≤6) and follow‐up interviews 6–10 months post‐diagnosis (N = 1057). Among men remaining on AS for at least 12 months (N = 601), we compared those who continued on AS (N = 515) versus men who underwent delayed AT (N = 86) between 13 and 24 months, using Cox proportional hazards models. Results Delayed AT was predicted by time dependent PSA levels (≥10 vs. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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