Effects of almond intake on oxidative stress parameters: A systematic review and meta-analysis of clinical trials

Autor: Bingfeng Luo, Walid Theib Mohammad, Abduladheem Turki Jalil, Marwan Mahmood Saleh, Muataz Mohammed Al-Taee, Mohammad Y. Alshahrani, Naseer Mihdi Mohammed, Ammar Heydani
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Complementary Therapies in Medicine, Vol 73, Iss , Pp 102935- (2023)
Druh dokumentu: article
ISSN: 0965-2299
DOI: 10.1016/j.ctim.2023.102935
Popis: Background and aims: Several randomized controlled trials (RCTs) have shown that almonds can improve oxidative stress indices, but the results are controversial. Therefore, the goal of this research was to carry out a systematic review and meta-analysis of all RCTs that evaluated the effect of almonds on selected oxidative stress indices. Methods: A systematic search was conducted up to April 2022 on PubMed, Scopus, Web of Science, and Google Scholar. We have selected the studies that investigated the effects of almonds on malondialdehyde (MDA), and oxidized low-density lipoprotein (Ox-LDL) levels in adults. Data were pooled by using the random-effects model. The risk of bias in individual studies was assessed using the Cochrane Collaboration risk of bias tool. Results: Seven RCTs involving 424 participants were analyzed. The results indicated that almond intake led to a significant decrease in MDA levels (WMD: − 6.63 nmol/ml; 95 % CI: − 8.72 to − 4.54; P
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