| Autor: |
Afaf N. Abdel Rahman, Shimaa R. Masoud, Moustafa M.S. Fouda, Abdelwahab A. Abdelwarith, Elsayed M. Younis, Samah S. Khalil, Haidy T. Zaki, Ebaa Mohammed, Simon J. Davies, Rowida E. Ibrahim |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Aquaculture Reports, Vol 32, Iss , Pp 101692- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2352-5134 |
| DOI: |
10.1016/j.aqrep.2023.101692 |
| Popis: |
Recently, researchers in aquaculture become interested in green synthesized nanomaterials as a superior alternative to current conventional methodologies. The present work shows that Moringa oleifera synthesized magnetite nanoparticles (MS-Fe3O4NPs) might offer a possible substitute for common antibiotics to treat Aeromonas sobria infection in African catfish (Clarias gariepinus). MS-Fe3O4NPs demonstrated an in vitro antibacterial potential (21 mm inhibition zone) against A. sobria. The fish (n = 120; average body weight: 90 ± 3.5 g) were randomized into four groups (control, MS-Fe3O4NPs, A. sobria, and MS-Fe3O4NPs + A. sobria), where 1.2 mg/L of MS-Fe3O4NPs was used as bath treatment for seven-days. A. sobria infection caused substantial elevations in malondialdehyde, tumor necrosis factor-alpha, stress indices, and hepato-renal biomarkers as well as a lower survival rate. Moreover, an apparent depletion in the level of antioxidants, the protein profile, and immune indicators were the consequences of A. sobria infection. Surprisingly, treatment of A. sobria-infected fish with MS-Fe3O4NPs recovered these parameters. Hence, MS-Fe3O4NPs as a water additive show promise as an antibacterial treatment against A. sobria in fish. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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