Adult onset sporadic ataxias: a diagnostic challenge

Autor: Orlando Graziani Povoas Barsottini, Marcus Vinicius Cristino de Albuquerque, Pedro Braga Neto, José Luiz Pedroso
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Arquivos de Neuro-Psiquiatria, Vol 72, Iss 3, Pp 232-240 (2014)
Druh dokumentu: article
ISSN: 1678-4227
0004-282X
DOI: 10.1590/0004-282X20130242
Popis: Patients with adult onset non-familial progressive ataxia are classified in sporadic ataxia group. There are several disease categories that may manifest with sporadic ataxia: toxic causes, immune-mediated ataxias, vitamin deficiency, infectious diseases, degenerative disorders and even genetic conditions. Considering heterogeneity in the clinical spectrum of sporadic ataxias, the correct diagnosis remains a clinical challenge. In this review, the different disease categories that lead to sporadic ataxia with adult onset are discussed with special emphasis on their clinical and neuroimaging features, and diagnostic criteria.
Databáze: Directory of Open Access Journals