| Autor: |
Jia ZHANG, Kaiyun ZHANG, Tao CHEN, Juan ZHAO, Hongmei WANG, Yingfang XUE, Guohui ZHANG |
| Jazyk: |
čínština |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Pifu-xingbing zhenliaoxue zazhi, Vol 29, Iss 5, Pp 391-398 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1674-8468 |
| DOI: |
10.3969/j.issn.1674-8468.2022.05.002 |
| Popis: |
Objective To investigate the differences in the cutaneous microbiome between patients with primary acute guttate psoriasis and healthy controls. Methods We enrolled 18 patients with primary acute guttate psoriasis, including 9 patients with upper respiratory tract infection and 9 patients without upper respiratory tract infection, and 9 healthy controls. Skin swabs were collected from lesional and non-lesional skin of psoriatic patients and healthy controls. The 16S rDNA sequencing was used for analyzing the DNA samples and annotating the sequencing results. The differences in microbial species and community structure among the three groups were determined by bioinformatics and statistics analysis. Results At the Phylum level, the dominant species among the three groups were Firmicutes, Proteobacteria and Actinobacteria. There was no significant difference in α diversity analysis among the three groups (all P>0.05). There were significant differences in the composition of microbial community between the control group and the two groups of patients (both P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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