| Autor: |
Silvia L. Fialho, Bárbara R. Silvestrini, Juliana Vieira, Mayara R. B. Paiva, Luciana M. Silva, Fernando Chahud, Armando Silva-Cunha, Zelia M. Correa, Rodrigo Jorge |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
International Journal of Retina and Vitreous, Vol 6, Iss 1, Pp 1-4 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2056-9920 |
| DOI: |
10.1186/s40942-020-00236-x |
| Popis: |
Abstract The authors developed a retinoblastoma model using fresh harvested cells from an enucleated eye that were transplanted in chick embryos (chorioallantoic membrane model). The transplanted embryos were treated with escalating doses of Melphalan. This exploratory model was developed with the goal of testing drug sensitivity. Our findings suggest this tumor model could be employed to personalize treatment for patients with retinoblastoma, especially those with bilateral and more refractory disease. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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