| Autor: |
Qianrong Liang, Ningyu Zhu, Xiaoye Zheng, Xueyan Ding, Runzhen He, Hongsen Xu, Feifei Cao, Huili Xue, Fan Zhou, Tianlun Zheng |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Fishes, Vol 7, Iss 2, p 79 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2410-3888 |
| DOI: |
10.3390/fishes7020079 |
| Popis: |
The Chinese soft-shelled turtle (Pelodiscus sinensis) is an important aquatic species in southern China that is threatened by many serious diseases. Edwardsiella tarda is one of the highly pathogenic bacteria that cause the white abdominal shell disease. Yet, little is known about the immune and metabolic responses of the Chinese soft-shelled turtle against E. tarda infection. In the paper, gene expression profiles in the turtle liver were obtained to study the immune responses and metabolic regulations induced by E. tarda infection using RNA sequencing. A total of 3908 differentially expressed unigenes between the experimental group and the control group were obtained by transcriptome analysis, among them, were the significantly upregulated unigenes and downregulated unigenes 2065 and 1922, respectively. Further annotation and analysis revealed that the DEGs were mainly enriched in complement and coagulation cascades, phagosome, and steroid hormone biosynthesis pathways, indicating that they were mainly associated with defense mechanisms in the turtle liver against E. tarda four days post infection. For the first time, we reported on the gene profile of anti-E. tarda response in the soft-shelled turtle, and our research might provide valuable data to support further study on anti-E. tarda defense mechanisms in turtles. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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