| Autor: |
Jeziel Basso, Juliana Beust de Lima, Marina Bessel, Santiago Alonso Tobar Leitão, Thais Machado Baptista, Sergio Roithmann, Eduardo Franco Carvalhal, Caio da Silva Schmitt, Ivan Morzoletto Pedrollo, Alice Schuch, Antonio Atalibio Hartmann, Carmen Liane Neubarth Estivallet, Guilherme Behrend Silva Ribeiro, Ricardo Andre Zordan, Pedro Isaacsson Velho |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Urology, Vol 23, Iss 1, Pp 1-6 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2490 |
| DOI: |
10.1186/s12894-023-01380-w |
| Popis: |
Abstract Background Prostate cancer exhibits a very diverse behaviour, with some patients dying from the disease and others never needing treatment. Active surveillance (AS) consists of periodic PSA assessment (prostate-specific antigen), DRE (digital rectal examination) and periodic prostate biopsies. According to the main guidelines, AS is the preferred strategy for low-risk patients, to avoid or delay definitive treatment. However, concerns remain regarding its applicability in certain patient subgroups, such as African American men, who were underrepresented in the main cohorts. Brazil has a very racially diverse population, with 56.1% self-reporting as brown or black. The aim of this study is to evaluate and validate the AS strategy in low-risk prostate cancer patients following an AS protocol in the Brazilian public health system. Methods This is a multicentre AS prospective cohort study that will include 200 patients from all regions of Brazil in the public health system. Patients with prostate adenocarcinoma and low-risk criteria, defined as clinical staging T1–T2a, Gleason score ≤ 6, and PSA |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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