Extraocular Sebaceous Carcinoma in the Lower Back: Rare Presentation of a Great Masquerader

Autor: Gurpreet Kaur Walia, Sai Nagavalli, Ramanjit Singh Akal, Surjeet Dwivedi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: CHRISMED Journal of Health and Research, Vol 11, Iss 2, Pp 125-126 (2024)
Druh dokumentu: article
ISSN: 2348-3334
2348-506X
DOI: 10.4103/cjhr.cjhr_49_24
Popis: Malignant adnexal tumors of the skin are rare. Sebaceous carcinoma (SC) is an aggressive malignant tumor of the sebaceous glands. It is traditionally classified into periocular and extraocular types. We present a rare case of extraocular SC of a 38-year-old female who presented with nontender swelling over the right flank for 1 year. Clinically, it was diagnosed with a sebaceous cyst. The tumor was excised and sent for histopathological examination. Sections showed sheets and lobules of tumor cells separated by fibrovascular stroma. Individual tumor cells were atypical basaloid to clear cells with prominent pleomorphism. Mitosis was brisk with areas of necrosis. On immunohistochemistry, the tumor cells were focally positive for epithelial membrane antigen and negative for S100 and PAX8 with a high Ki-67 index of 80%. Her postoperative period and follow-up for 1 year have been uneventful. This case is being reported for its rarity.
Databáze: Directory of Open Access Journals
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