The effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study

Autor: Michael S. Tanner, Deborah De Guingand, Maya Reddy, Saskia Rowson, Daniel L. Rolnik, Fabricio Da Silva Costa, Mary-Ann Davey, Ben W. Mol, Euan M. Wallace, Kirsten R. Palmer
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Hypertension in Pregnancy, Vol 40, Iss 4, Pp 336-345 (2021)
Druh dokumentu: article
ISSN: 1064-1955
1525-6065
10641955
DOI: 10.1080/10641955.2021.1991371
Popis: Objective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia. Methods: A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes. Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications. Conclusion: Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.
Databáze: Directory of Open Access Journals