Mimics of scleroderma

Autor: Kaveri K Nalianda, Mithun M Rathen, Soumya Jagadeesan, D Padmanabha Shenoy
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Indian Journal of Rheumatology, Vol 12, Iss 6, Pp 171-179 (2017)
Druh dokumentu: article
ISSN: 0973-3698
0973-3701
Popis: Systemic sclerosis is a rare autoimmune connective tissue disorder characterised typically by tightening and tethering of skin. However, several other disorders are also characterised by hardening and thickening of skin. These mimics can be potentially confused with systemic sclerosis, leading to a misdiagnosis. This review describes the aetiopathogenesis, clinical features and treatment of Morphea (localised scleroderma), Scleredema, Scleromyxoedema, Eosinophilic fasciitis, Nephrogenic Systemic Fibrosis, Diabetic Cheiroarthropathy, chronic GVHD, POEMS syndrome and drug induced scleroderma like illness. A careful and thorough clinical assessment is essential in order to differentiate these mimics from each other and from systemic sclerosis, establish the diagnosis, and initiate appropriate treatment.
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