Effect of intrauterine infusion of platelet-rich plasma for women with recurrent implantation failure: a systematic review and meta-analysis

Autor: Haiyu Deng, Suqing Wang, Zhijie Li, Lingfei Xiao, Ling Ma
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology, Vol 43, Iss 1 (2023)
Druh dokumentu: article
ISSN: 0144-3615
1364-6893
01443615
DOI: 10.1080/01443615.2022.2144177
Popis: This study evaluated the effect of intrauterine perfusion of autologous platelet-rich plasma (PRP) on pregnancy outcomes in women with recurrent implantation failure (RIF). Key biomedical databases were searched to identify relevant clinical trials and observational studies. Outcomes included clinical pregnancy rate, chemical pregnancy rate, implantation rate, live birth rate, and abortion rate. Data was extracted from ten studies (six randomised controlled trials, four cohort studies) involving 1555 patients. Pregnancy outcomes were improved in women treated with PRP compared to controls: clinical pregnancy rate (RR = 1.96, 95% CI [1.67, 2.31], p
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