Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil

Autor: Nina Ni, Marc A. Goldberg, Ralph C. Eagle, Christopher J. Rapuano, Julia A. Haller
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Case Reports in Ophthalmological Medicine, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 2090-6722
2090-6730
19973349
DOI: 10.1155/2015/325485
Popis: Purpose. To present the clinical and histopathologic correlation of two cases of epithelial downgrowth (EDG) after prior intraocular surgery. Methods. Observational case reports. Results. We present two cases of EDG occurring after intraocular surgery. In both cases, after two anterior chamber injections of 5-fluorouracil (5FU), the area of EDG initially regressed. In Case 1, a limited area of EDG eventually recurred, and penetrating keratoplasty with cryotherapy was curative. In Case 2, subsequent corneal edema required Descemet-stripping automated endothelial keratoplasty, and the patient remained clinically free of EDG without further treatment. Conclusion. Intracameral 5FU may have a role in the treatment of EDG after intraocular surgery, though its precise utilization and impact remain to be defined.
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