Predicting and preventing sudden cardiac death in myocardial infarction patients

Autor: S. A. Boldueva, A. V. Shabrov, D. S. Lebedev, T. Ya. Burak, I. A. Leonova, M. V. Samokhvalova, V. S. Zhuk, E. G. Bykova
Jazyk: ruština
Rok vydání: 2008
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 7, Iss 3, Pp 56-62 (2008)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
Popis: Aim. To investigate sudden cardiac death (SCD) predictors in patients after myocardial infarction (MI), to develop the strategy of risk stratification and SCD prevention.Material and methods. In total, 420 patients were examined at Day 10-14 after MI; follow-up period lasted for 1-4 years. General clinical examination, echocardiography, 24-hour electrocardiography (ECG) monitoring, late ventricular potentials (LVP) detection, active orthostatic test (AOT), heart rate variability (HRV) assessment at baseline and during functional tests, as well as psychological testing, were performed. Some participants underwent coronarography and endocardial electrophysiological examination. SCD risk was assessed by Cox multi-factor analysis and Kaplan-Meier survival curve method.Results. According to Cox multivariate regression analysis, the most important predictors included the following six parameters: LVP, HRV reduction, left ventricular ejection fraction
Databáze: Directory of Open Access Journals