Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations

Autor: Elisa Varela, Miguel A. Muñoz-Lorente, Agueda M. Tejera, Sagrario Ortega, Maria A. Blasco
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms11739
Popis: Telomere shortening has been linked to some aspects of organismal ageing. Here the authors create chimaeric mice that contain a mix of cells with normal or unnaturally long telomeres, and show chimaeric mice are protected from some forms of ageing-associated cellular damage and have accelerated wound-healing.
Databáze: Directory of Open Access Journals