A new phenotypic classification system for dyslipidemias based on the standard lipid panel

Autor:	Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James D. Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis, Alan T. Remaley
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Cholesterol LDL Lipids Lipoproteins Genetics Cardiovascular disease Nutritional diseases. Deficiency diseases RC620-627
Zdroj:	Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-21 (2021)
Druh dokumentu:	article
ISSN:	1476-511X
DOI:	10.1186/s12944-021-01585-8
Popis:	Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophoresis/beta-quantification in a large number of subjects. The new lipoprotein phenotyping system identifies high-risk cardiovascular patients and helps direct clinical management. A major advance is that the new lipoprotein phenotypes are based on just the standard lipid panel, and thus can be automatically calculated by the clinical laboratory and widely implemented.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/00d7e07ea77947e29c74d7d4034f28c2 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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