1-year quality of life and health-outcomes in patients hospitalised with COVID-19: a longitudinal cohort study

Autor: Kate O’Brien, Liam Townsend, Joanne Dowds, Ciarán Bannan, Parthiban Nadarajan, Brian Kent, Niamh Murphy, Gráinne Sheill, Ignacio Martin-Loeches, Emer Guinan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Respiratory Research, Vol 23, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1465-993X
DOI: 10.1186/s12931-022-02032-7
Popis: Abstract Background Published studies suggest physical recovery from the COVID-19 is complex, with many individuals experiencing persistent symptoms. There is a paucity of data investigating the longer-term trajectory of physical recovery from COVID-19. Methods A prospective longitudinal design was utilised to investigate the impact COVID-19 has on physical functioning at 10-weeks (T1), 6-months (T2) and 1-year (T3) post-hospital discharge. Objective measures of recovery included 6-Minute Walk Test Distance (6MWTD), frailty (Clinical Frailty Scale), quantification of falls following hospital-discharge, return to work status and exercise levels. Subjective markers included symptoms (COVID-19-Specific Patient Concerns Assessment), fatigue (Chalder Fatigue Score) and health-related quality of life (HrQOL) [Short-Form-36 Health Survey Questionnaire (SF-36-II)]. Univariate analysis was performed using t-test, Wilcoxon rank-sum, and Chi-squared test, paired analysis using one-way analysis of variance and Krustal Wallis testing and correlation analysis with Spearman correlation tests. Results Sixty-one subjects participated. Assessments were conducted at a median of 55 days(T1), 242 days(T2), and 430 days(T3) following hospital-discharge. 6MWTD improved significantly overtime (F = 10.3, p
Databáze: Directory of Open Access Journals
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