2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema

Autor: Bowen Tom, Cicardi Marco, Farkas Henriette, Bork Konrad, Longhurst Hilary J, Zuraw Bruce, Aygoeren-Pürsün Emel, Craig Timothy, Binkley Karen, Hebert Jacques, Ritchie Bruce, Bouillet Laurence, Betschel Stephen, Cogar Della, Dean John, Devaraj Ramachand, Hamed Azza, Kamra Palinder, Keith Paul K, Lacuesta Gina, Leith Eric, Lyons Harriet, Mace Sean, Mako Barbara, Neurath Doris, Poon Man-Chiu, Rivard Georges-Etienne, Schellenberg Robert, Rowan Dereth, Rowe Anne, Stark Donald, Sur Smeeksha, Tsai Ellie, Warrington Richard, Waserman Susan, Ameratunga Rohan, Bernstein Jonathan, Björkander Janne, Brosz Kristylea, Brosz John, Bygum Anette, Caballero Teresa, Frank Mike, Fust George, Harmat George, Kanani Amin, Kreuz Wolfhart, Levi Marcel, Li Henry, Martinez-Saguer Inmaculada, Moldovan Dumitru, Nagy Istvan, Nielsen Erik W, Nordenfelt Patrik, Reshef Avner, Rusicke Eva, Smith-Foltz Sarah, Späth Peter, Varga Lilian, Xiang Zhi
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Allergy, Asthma & Clinical Immunology, Vol 6, Iss 1, p 24 (2010)
Druh dokumentu: article
ISSN: 1710-1492
1710-1484
DOI: 10.1186/1710-1492-6-24
Popis: Abstract Background We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art review: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Objective To update the International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema (circa 2010). Methods The Canadian Hereditary Angioedema Network (CHAEN)/Réseau Canadien d'angioédème héréditaire (RCAH) http://www.haecanada.com and cosponsors University of Calgary and the Canadian Society of Allergy and Clinical Immunology (with an unrestricted educational grant from CSL Behring) held our third Conference May 15th to 16th, 2010 in Toronto Canada to update our consensus approach. The Consensus document was reviewed at the meeting and then circulated for review. Results This manuscript is the 2010 International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema that resulted from that conference. Conclusions Consensus approach is only an interim guide to a complex disorder such as HAE and should be replaced as soon as possible with large phase III and IV clinical trials, meta analyses, and using data base registry validation of approaches including quality of life and cost benefit analyses, followed by large head-to-head clinical trials and then evidence-based guidelines and standards for HAE disease management.
Databáze: Directory of Open Access Journals
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