Assessment of subclinical renal dysfunction in post COVID-19 patients

Autor: Peter AtefMikhael, Salah Said Naga, Sherif Aziz Zaki, Amira Hussein Mohamed
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Alexandria Journal of Medicine, Vol 60, Iss 1, Pp 76-81 (2024)
Druh dokumentu: article
ISSN: 20905068
2090-5076
2090-5068
DOI: 10.1080/20905068.2024.2333595
Popis: Introduction Kidney damage in COVID-19 is common and may lead to CKD. Early recognition of progression is mandatory, so there is a need for sensitive markers of kidney damage. Renal functional reserve (RFR) is described as the ability of the kidneys to augment their function in special situations.Aim of Work Was to assess subclinical renal dysfunction post-COVID-19.Methods This cross-sectional study investigates 31 patients previously infected with COVID-19 within 2–3 months and 31 healthy subjects with matched age and sex. Assessment of RFR was done by calculating the estimated GFR using the CKD-EPI equation before and 2 hours after 80 g protein load by intravenous infusion.Results RFR was significantly lower in post-COVID-19 patients (mean of 11.19 ± 4.76) than the control (mean of 25.81 ± 4.42, p
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