Autor: |
S T Kunitake, K J La Sala, J P Kane |
Jazyk: |
angličtina |
Rok vydání: |
1985 |
Předmět: |
|
Zdroj: |
Journal of Lipid Research, Vol 26, Iss 5, Pp 549-555 (1985) |
Druh dokumentu: |
article |
ISSN: |
0022-2275 |
DOI: |
10.1016/S0022-2275(20)34341-8 |
Popis: |
Among the apoA-I-containing lipoproteins isolated by selected-affinity immunosorption from human serum and plasma, we have identified a subpopulation which, unlike the bulk of high density lipoproteins, has pre-beta electrophoretic mobility. This pre-beta subpopulation can be observed directly in fresh plasma by immunoelectrophoresis. It contains phospholipid and free and esterified cholesterol, but protein constitutes 90% of its mass. Apolipoprotein A-I is the predominant apolipoprotein in this subpopulation; apolipoprotein A-II and the B lipoproteins are not detected. The protein moiety of this subpopulation exhibits markedly lower helicity than that of high density lipoproteins isolated by ultracentrifugation. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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