Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Autor: Shin Murakami, Tomoya Kitamura, Jin Suzuki, Ryouta Sato, Toshiki Aoi, Marina Fujii, Hiromichi Matsugo, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Masayuki Shimojima, Taisuke Horimoto
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 26, Iss 12, Pp 3025-3029 (2020)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2612.203386
Popis: Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.
Databáze: Directory of Open Access Journals