Vitamin B6 Neonatal Toxicity

Autor: Andrea Guala, Giulia Folgori, Micaela Silvestri, Michelangelo Barbaglia, Cesare Danesino
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Case Reports in Pediatrics, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 2090-6811
DOI: 10.1155/2022/3171351
Popis: Vitamin B6 is a micronutrient required by the body. It acts as a coenzyme in biochemical reactions. Vitamin B6 toxicity is not caused by the intake of food-based sources. The few reported cases of vitamin B6 toxicity are always caused by overdosing of nutritional supplements. Chronic toxicity typically occurs with peripheral neuropathy such as paraesthesia, ataxia, and imbalance, paradoxically mimicking vitamin B6 deficiency. However, the prognosis is favorable, and symptoms usually show improvement once excessive vitamin B6 levels return to the physiological range. We report a newborn presenting with diffuse tremor at birth, interpreted as secondary to the mother's intake of high doses of a supplement containing vitamin B6 during pregnancy and breastfeeding. As expected, the newborn’s serum levels of vitamin B6 were high. The tremors disappeared when the maternal supplement was stopped.
Databáze: Directory of Open Access Journals
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