Acute carbamazepine toxicity in a child: A case report

Autor:	Manjinder Singh Randhawa, Prateek Sharma, Suresh Kumar Angurana, Arun Bansal
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	activated charcoal antiepileptic drug toxicity carbamazepine extracorporeal removal multidose activated charcoal pediatric toxicity Pediatrics RJ1-570
Zdroj:	Journal of Pediatric Critical Care, Vol 8, Iss 6, Pp 299-301 (2021)
Druh dokumentu:	article
ISSN:	2349-6592 2455-7099
DOI:	10.4103/jpcc.jpcc_65_21
Popis:	Carbamazepine is a commonly prescribed antiepileptic drug with a potential to cause fatal toxicity in acute overdose in children. Symptoms of acute toxicity include central nervous system depression, seizures, anticholinergic toxidrome, and arrhythmias. We report a 5 year old male child with accidental carbamazepine toxicity treated sussessfully with good suppotrive management. Intestinal decontamination therapies may be beneficial if used at the appropriate time. Multidose activated charcoal may be used if multiple controlled release tablets are ingested. Extracorporeal therapies for drug removal may be required in life-threatening toxicity to reduce plasma drug levels and hasten recovery. Appropriate and timely management leads to excellent neurological outcome.
Databáze:	Directory of Open Access Journals
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