High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli
| Autor: | Tomoya Maeda, Junichiro Iwasawa, Hazuki Kotani, Natsue Sakata, Masako Kawada, Takaaki Horinouchi, Aki Sakai, Kumi Tanabe, Chikara Furusawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 32844840 |
| DOI: | 10.1038/s41467-020-19713-w |
| Popis: | Understanding evolutionary constraints in antibiotic resistance is crucial for prediction and control. Here, the authors use high-throughput laboratory evolution of Escherichia coli alongside machine learning to identify trade-off relationships associated with drug resistance. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|