The structural diversity of ibuprofen sustained-release pellets on the same goal of bioequivalence consistency

Autor:	Zeying Cao, Ningyun Sun, Hongyu Sun, Jun Liu, Jing Li, Dezhong Bi, Caifen Wang, Li Wu, Xianzhen Yin, Tiqiao Xiao, Rui Yang, Mingdi Xu, Wei Wu, Jiwen Zhang
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Consistency evaluation Bioequivalence Three-dimensional structures Internal structure parameters Ibuprofen sustained-release pellets Micro-computed tomography Materials of engineering and construction. Mechanics of materials TA401-492
Zdroj:	Materials & Design, Vol 217, Iss , Pp 110583- (2022)
Druh dokumentu:	article
ISSN:	0264-1275
DOI:	10.1016/j.matdes.2022.110583
Popis:	The consistency evaluation, which is largely unexplored is crucial in regulating the quality and efficacy of generic drugs. In this report, after generic ibuprofen (IBU) sustained-release pellets were developed and validated as bioequivalent to the reference list drug (RLD) in 48 healthy human volunteers (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/001a6760537543089283c2fc8cb43edb Zobrazit plný text záznamu Full Text from ScienceDirect View record in DOAJ