Trends and age, sex, and race disparities in time to second primary cancer from 1990 to 2019

Autor: Tiffany H. Leung, Aya El Helali, Xiaofei Wang, James C. Ho, Herbert Pang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Medicine, Vol 12, Iss 24, Pp 22316-22324 (2023)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.6785
Popis: Abstract Background Despite the growth in primary cancer (PC) survivors, the trends and disparities in this population have yet to be comprehensively examined using competing risk analysis. The objective is to examine trends in time to second primary cancer (SPC) and to characterize age, sex, and racial disparities in time‐to‐SPC. Methods A retrospective analysis was conducted based on Surveillance, Epidemiology, and End Results (SEER). Two datasets for this study are (1) the discovery dataset with patients from SEER‐8 (1990–2019) and (2) the validation dataset with patients from SEER‐17 (2000–2019), excluding those in the discovery dataset. Patients were survivors of lung, colorectal, breast (female only), and prostate PCs. Results The 5‐year SPC cumulative incidences of lung PC increased from 1990 to 2019, with the cumulative incidence ratio being 1.73 (95% confidence intervals [CI], 1.64–1.82; p
Databáze: Directory of Open Access Journals
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