Impact of SARS‐CoV‐2 infection on pain crisis and acute chest syndrome in patients with sickle cell anemia: A retrospective multi‐cohort study based on US national data from 2020 to 2022

Autor: Juan Alvarado, Keval Yerigeri, Anita Boakye, Christina Randolph, Aparna Roy, Grace Onimoe
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: eJHaem, Vol 5, Iss 2, Pp 299-307 (2024)
Druh dokumentu: article
ISSN: 2688-6146
DOI: 10.1002/jha2.840
Popis: Abstract COVID‐19 infection has been a significant contributor to global morbidity and mortality, especially among those patients with chronic diseases. The Centers for Disease Control and Prevention have classified sickle cell disease (SCD) as a condition that increases the risk of severe illness from COVID‐19 infection. A retrospective study was conducted using the TRiNetX health research network database to identify SCA patients ( HbSS, Sbeta‐thalassemia zero) who had SARS‐CoV‐2 infection over 2 years; these were compared with similar patients who did not have the infection in terms of demographics, pain control, and laboratory parameters COVID‐19 illness impacts [ain crises and ACS, and prior vaccination against influenza and COVID‐19 may represent a protective factor for developing pain crises.
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