MRI and three dimensional ultrasonography in the assessment of pulmonary hypoplasia in fetuses with urinary tract anomalies

Autor: Mariam Raafat, Mona El-Kalioubie, Sahar Mahmoud Mansour
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: The Egyptian Journal of Radiology and Nuclear Medicine, Vol 47, Iss 4, Pp 1753-1764 (2016)
Druh dokumentu: article
ISSN: 0378-603X
DOI: 10.1016/j.ejrnm.2016.06.014
Popis: Purpose: To analyze the correlation and agreement between three dimensional (3D) US and MRI in the assessment of pulmonary volumes of fetuses with different types of urinary tract malformations (UTM) and high-risk of pulmonary hypoplasia (PH). Patients and methods: Thirty-nine fetuses with various UTM, at risk for PH were involved in this cross-sectional study. 3D volume US data sets of the fetal lungs were acquired. The right, left and total lung volumes were calculated separately using the virtual organ computer-aided analysis (VOCAL) method with a 30° rotation. MRI of fetal lung was obtained with assessment of signal intensity and lung volumetry. Comparison between mean lung volumes was performed using unpaired t test. Agreement between the 3D-US and MRI methods was done using Cohen kappa test. Results: Good agreement was detected between the two methods (Kappa = 0.629, p = 0.001). The measured lung volumes by 3D-US were smaller than those measured by MRI (p > 0.05, non-significant). MRI showed greater specificity, PPV and diagnostic accuracy (100% each) than 3D-US (50%, 88.9% and 90% respectively). Conclusion: There is a good concordance between 3D-US and MRI in the evaluation of PH in fetuses with UTM. MRI could be reserved for borderline cases of pulmonary hypoplasia and the difficult diagnostic situations.
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