Isolated remote site musculoskeletal Mycobacterium bovis infections after BCG immunisation in immunocompetent children

Autor: Jiawen Fong, Dawn Sinn Yii Chia, Darryl Ee Ming Chew, Kenneth Pak Leung Wong
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Annals, Academy of Medicine, Singapore, Vol 53, Iss 8, Pp 514-518 (2024)
Druh dokumentu: article
ISSN: 2972-4066
DOI: 10.47102/annals-acadmedsg.202449
Popis: The Bacillus Calmette–Guerin (BCG) vaccine, derived from wild-type Mycobacterium bovis, is administered in an attenuated form to prevent Mycobacterium tuberculous (MTB) infections in children residing in endemic regions. Since the introduction of the Singapore Tuberculosis Elimination Programme in 1997—specifying mandatory BCG-immunisation at birth—the incidence fell drastically to 32.6 per 100,000 population in 2021,1 with the paediatric population contributing 2.1% of infections.2
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