| Autor: |
Feng, Xu, Li, Guo-yang, Jiang, Yuxuan, Shortt-Nguyen, Owen, Yun, Seok-Hyun |
| Rok vydání: |
2024 |
| Předmět: |
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| Druh dokumentu: |
Working Paper |
| Popis: |
Lens tension is essential for accommodative vision but remains challenging to measure with precision. Here, we present an optical coherence elastography (OCE) technique that quantifies both the tension and elastic modulus of lens tissue and capsule. This method derives mechanical parameters from surface wave dispersion across a critical frequency range of 1-30 kHz. Using isolated lenses from six-month-old pigs, we measured intrinsic anterior capsular tensions of 0-20 kPa and posterior capsular tensions of 40-50 kPa, induced by intra-lenticular pressure at the cortical surface. Young's modulus (E) was 1.9 MPa for anterior capsules and 1.2 MPa for posterior capsules. Tensions in cortical tissue (E ~ 10 kPa) were below 1 kPa. Biaxial zonular stretching (~4% strain) increased anterior capsular tension from near zero to 64 kPa. This acousto-optical method holds significant promise for diagnosing and managing accommodative dysfunctions through lens mechanics assessment in clinical settings. |
| Databáze: |
arXiv |
| Externí odkaz: |
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